Development of industrially used processes:
- Total synthesis of steroids (industrial application of a synthetic method for the preparation of 2-alkylcycloalkan-1,3-diones, worldwide)
- Total synthesis of prostaglandins
Classes of compounds:
- Aliphatic and cycloaliphatic compounds (e.g. steroid hormones, vitamin D3-metabolites, cardenolides, prostaglandins)
- Aromatic compounds e.g. diaryl ethers)
- Heterocyclic compounds (nitrogen, sulfur and/or oxygen-containing mono- and bicyclic systems, lactones)
- Nucleosides (including carbocyclic nucleosides)
- Monosaccharides (selective protecting group techniques)
- Organic phosphorus compounds
Special methods and techniques
- Enzyme assisted catalysis in organic synthesis (enantio- and regioselective acylation, resolution of racemates, desymmetrisations)
- Organometallic compounds in organic synthesis (CC-bond formation, titanium- and palladium-assisted reactions, organozinc and organoindium compounds)
- Electrochemical methods (reduction, preparation of organometallic compounds, application of sacrificial anodes)
- Protecting group techniques in multi-step syntheses (e.g. in prostaglandin syntheses)
- Catalysis, oxidations, reductions
- Halogenation of aliphatic compounds
- Radical reactions
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